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| Catalogue | Size | Price | Quantity | |
|---|---|---|---|---|
| LC9897-4L | 4L | $199.62 | ||
| LC9897-4x4L | 4X4L | $794.62 |
Acetonitrile for LCMS Grade | CAS: 75-05-8 | M.F: CH3CN | MW: 41.05, Buy now for reliable and reproducible results from LiChrom HPLC Solvents Dawnscientific.
Acetonitrile, a very polar and volatile organic solvent, is used as a solvent in many industrial processes for liquid chromatography-mass spectrometry (LC-MS). It is a clear, colorless liquid with an ether-like aromatic smell. It is otherwise known simply as methyl cyanide (MeCN), but also by other names including cyanomethane, ethyl nitrile, and methane carbonitrile. It has a chemical formula of CH3CN and a structural representation of H3C-C?N. Acetonitrile is used mainly as a mobile phase in liquid chromatography.
Applications of Acetonitrile for LC-MS
Key Features of Acetonitrile for LC-MS
High purity with low water content
Provides improved ionization efficiency and less interferenceLow UV absorbance
Suitable for UV and MS detectionMore reproducibility of results
Eliminates the requirement for repeat analysisMinimum rework and maximum accuracy
Saves cost and time in analytical laboratoriesGeneral Description
Acetonitrile for LC-MS Grade is a high-quality solvent that finds extensive applications in analytical and preparative chromatography, especially in Liquid Chromatography–Mass Spectrometry (LC-MS). Having been identified by CAS No. 75-05-8, the high-purity acetonitrile (Molecular Formula: CH?CN, Molecular Weight: 41.05) provides very low water content, low UV absorbance, and minimal impurities and thus is the best option for laboratories requiring accuracy, consistency, and minimal background interference.
Looking for where to buy Acetonitrile for LC-MS Grade or how much it costs? Visit Dawn Scientific, your reliable source of analytical reagents and solvents. We offer rapid shipping, complete COAs and SDSs, and individualized service to research institutions, pharmaceutical laboratories, and industrial clients.
Purchase competitive prices of Acetonitrile for LC-MS Grade from Dawn Scientific. Price depends on volume and package type. Request a quote on bulk quantities and avail special discounts for bulk orders.
Make precise measurements, achieve better reproducibility, and reduce background noise on all analyses. Buy Acetonitrile for LC-MS Grade from Dawn Scientific today and benefit from the performance and quality trusted by professionals worldwide.
About Brand
Lichrom is one of the excellent quality products specially designed for Liquid Chromatography. LiChrom series products are ideal for all types of Liquid Chromatography. LiChrom is your entirety HPLC analysis reagent requirements in pharmaceutical analysis, biopharma research, and environmental analysis. in addition to High Purity HPLC solvents “Lichrom” offers a wide range of HPLC grade buffer salts, and Ion pair reagents to ensure consistent and reproducible performance in your analysis.
Why Dawn Scientific?
In addition to our specialty product lines, Dawn Scientific offers a comprehensive range of laboratory supplies and scientific products, including laboratory chemicals, reagents, analytical standards, solutions, buffers, biological stains, indicators, laboratory equipment, instruments, consumables, and much more.
For complete product information, technical resources, and our full catalog, please browse other categories on our website dawnscientific.com.
If you have any questions or would like assistance selecting the right products for your application, our knowledgeable team is ready to help. Contact us at 1-800-DAWN-SCI (1-800-329-6724) or email sales@dawnscientific.com. We look forward to serving your laboratory and research needs.
Acetonitrile for LC-MS is used as a high-purity solvent and mobile phase in LC-MS, UHPLC-MS, peptide analysis, pharmaceutical testing, and analytical research applications.
LC-MS grade Acetonitrile undergoes additional testing for trace metals, ionic contaminants, and background interference to ensure better mass spectrometry sensitivity and cleaner spectra.
A low ionic background improves ionization efficiency, reduces ion suppression, and enhances sensitivity in mass spectrometry analysis.
Yes, high-purity LC-MS-grade acetonitrile helps produce cleaner baselines, lower background noise, and improved signal-to-noise ratios in analytical methods.
Acetonitrile is widely used in peptide and biomolecule analysis because it offers excellent volatility, efficient chromatographic separation, and compatibility with electrospray ionization (ESI).
LC-MS grade Acetonitrile is typically supplied with purity of ?99.9% and extremely low trace contaminant levels for sensitive analytical applications.
It should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from moisture, heat, and ignition sources.
Acetonitrile for LC-MS is commonly available in 4 L and bulk packaging options for laboratory and industrial use.
LC-MS grade solvents help minimize contamination, reduce background interference, and improve reproducibility in high-sensitivity analytical methods.
Dawn Scientific offers high-purity LC-MS grade Acetonitrile with reliable consistency, low impurity levels, and dependable analytical performance for advanced laboratory applications.

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