


Acetonitrile HPLC Plus, ≥99.9%, Part Number 34998-4X4L-SA Buy now from Sigma-Aldrich at Dawnscientific.
Acetonitrile (MeCN) HPLC Plus grade from Sigma-Aldrich delivers ≥99.9% purity for the most demanding laboratory applications. With a high dielectric constant of 37.5 and exceptional UV transparency, this reagent-grade solvent is widely used in HPLC, mass spectrometry, UV, IR, GC, TLC, GPC, pesticide residue analysis, and RNA/DNA synthesis and purification. Filtered through a 0.2 μm filter and available in an advanced M-Bottle design for safer solvent handling, it is available at Dawn Scientific for laboratories requiring the highest analytical standards.
Key Features
Specifications Table
| Parameter | Details |
|---|---|
| Supplier | Sigma-Aldrich |
| Product Name | Acetonitrile, HPLC Plus |
| Grade | HPLC Plus |
| Assay | ≥99.9% |
| Form | Liquid |
| Boiling Point | 81–82 °C (lit.) |
| Melting Point | −45 °C (lit.) |
| Density | 0.786 g/mL at 25 °C (lit.) |
| Refractive Index | n20/D 1.344 (lit.) |
| Vapor Pressure | 72.8 mmHg at 20 °C |
| Vapor Density | 1.41 (vs air) |
| Autoignition Temp. | 973 °F |
| Explosive Limit | 16% |
| Parameter | Details |
|---|---|
| Baseline Drift | ≤12 mAU at 210 nm |
| HPLC Gradient | ≤0.2 mAU at 254 nm, ≤1 mAU at 210 nm |
| Water Content | ≤0.01% (Karl Fischer) |
| Non-volatile Matter | ≤0.0002% |
| Free Acid (as CH3COOH) | ≤0.001% |
| Free Alkali (as NH3) | ≤0.0001% |
| Halogenated Residue | ≤10 ng/L (as heptachlor epoxide) |
| Fluorescence at 254 nm | ≤0.5 ppb (quinine) |
| Fluorescence at 365 nm | ≤0.5 ppb (quinine) |
| Filter | 0.2 μm filtered |
| SMILES | CC#N |
| InChI Key | WEVYAHXRMPXWCK-UHFFFAOYSA-N |
| Packaging | M-Bottle with advanced sealing technology |
| Technique(s) | HPLC, IR spectroscopy |
Applications & Uses
Sigma-Aldrich Acetonitrile HPLC Plus is widely used across analytical and research laboratory workflows, including:
Why Buy from Dawn Scientific?
Dawn Scientific is built on a commitment to certified quality and dependable supply. When you order through Dawn Scientific, you receive:
In addition to our specialty product lines, Dawn Scientific offers a comprehensive range of laboratory supplies and scientific products, including laboratory chemicals, reagents, analytical standards, solutions, buffers, biological stains, indicators, laboratory equipment, instruments, consumables, and much more.
For complete product information, technical resources, and our full catalog, please browse other categories on our website ( www.dawnscientific.com.)
If you have any questions or would like assistance selecting the right products for your application, our knowledgeable team is ready to help. Contact us at 1-800-DAWN-SCI or email sales@dawnscientific.com. We look forward to serving your laboratory and research needs.
Frequently Asked Questions (FAQs)
Sigma-Aldrich Acetonitrile HPLC Plus grade has a minimum assay purity of ≥99.9%, making it suitable for the most demanding HPLC and analytical applications.
This acetonitrile is suitable for HPLC, mass spectrometry, UV, IR, GC, TLC, GPC, pesticide residue analysis, and RNA/DNA synthesis and purification.
Yes, the product is filtered through a 0.2 μm filter to ensure consistent purity and performance in sensitive analytical workflows.
It is available in Sigma-Aldrich's M-Bottle, which features advanced sealing technology to eliminate leaks and ensure safer, more convenient solvent handling.
Sigma-Aldrich Acetonitrile HPLC Plus is available for purchase online through Dawn Scientific, an authorized supplier offering genuine products with fast, reliable delivery across the USA.


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