H225 – Highly Flammable
H302 – Harmful if swallowed
H319 – Causes serious eye irritation.



| Catalogue | Size | Price | Quantity | |
|---|---|---|---|---|
| LC9855-4L | 4L | $119.62 | ||
| LC9855-4x4L | 4X4L | $349.62 |
Acetonitrile HPLC grade is a clear, colorless liquid with an ether-like odor and a sweet, burnt taste. It is often abbreviated Methyl Cyanide(MeCN). Its chemical formula is CH₃CN and structure is H₃C−C≡N. It is produced mainly as a byproduct of acrylonitrile manufacture. Acetonitrile HPLC solvent is free from UV-absorbing impurities that ensures consistent result in gradient analysis with noise-free baselines and minimum drift.
Properties
| Quality Level | 100 |
| Vapor Density | 1.41 (vs air) |
| Vapor Pressure | 72.8 mmHg (20 °C) |
| Assay | ≥99.9% |
| Form | Liquid |
| Autoignition Temperature | 973 °F |
| Explosive Limit | 0.16 |
| Technique(s) | HPLC: suitable |
| Impurities | ≤0.0002% free alkali (as NH3) ≤0.0005% Residue on evaporation ≤0.001% free acid (as CH3COOH) ≤0.02% water |
| Refractive Index | n20/D 1.344 (lit.) |
| Boiling Point | 81-82 °C (lit.) |
| Melting Point | −45 °C (lit.) |
| Density | 0.786 g/mL at 25 °C (lit.) |
| UV Absorption | λ: 190 nm Amax: ≤1.00 λ: 195 nm Amax: ≤0.10 λ: 200 nm Amax: ≤0.002 λ: 210 nm Amax: ≤0.015 λ: 220 nm Amax: ≤0.010 λ: 230 nm Amax: ≤0.0044 λ: 235 nm Amax: ≤0.0044 λ: 250 nm Amax: ≤0.0044 λ: 400 nm Amax: ≤0.0044 |
| SMILES String | CC#N |
| InChI | 1S/C2H3N/c1-2-3/h1H3 |
| InChI Key | WEVYAHXRMPXWCK-UHFFFAOYSA-N |
Description
Acetonitrile HPLC is a premium-grade solvent known for its exceptional purity and reliability in liquid chromatography applications. At Dawn Scientific, we proudly offer Acetonitrile HPLC (CAS No: 75-05-8, Molecular Formula: CH₃CN, Molecular Weight: 41.05 g/mol), ensuring superior performance in analytical and research settings.
Applications of Acetonitrile HPLC
Liquid
Chromatography
Provides superior separation and analysis in pharmaceutical, biopharma and environmental research
UV
Detection
Ensures precise UV/Vis
spectrophotometry and fluorimetry due to low absorbance characteristics
Organic
Synthesis
Functions as a solvent and
intermediate in complex chemical reactions
Analytical
studies
Used extensively in analytical
labs for precise analysis of composition
studies
Why Choose Dawn Scientific for Acetonitrile HPLC?
Register with us today and get discounts on bulk orders.
our LiChrom series, consisting of Acetonitrile HPLC, is ISO-crafted to give unmatched quality for all applications in liquid chromatography.
In addition to Acetonitrile HPLC, explore our catalog for HPLC-grade acids, bases, buffer Trusted Quality: our LiChrom series, consisting of Acetonitrile HPLC, is ISO-crafted to give unmatched quality for all applications in liquid chromatography.
salts, and ion-pair reagents.
Our teams are dedicated to your success through customized solutions and technical support.
Safety Information
H225 – Highly Flammable
H302 – Harmful if swallowed
H319 – Causes serious eye irritation.
About Dawn Scientific and LiChrom Products
Dawn Scientific is the exclusive distributor of LiChrom products, offering an extensive range of HPLC reagents and solvents. Explore our comprehensive catalog of lab supplies, chemicals, and instruments designed for precision and performance.
Why Dawn Scientific?
including laboratory chemicals, reagents, analytical standards, solutions, buffers, biological stains, indicators, laboratory equipment, instruments, consumables, and much more.
For complete product information, technical resources, and our full catalog, please browse other categories on our website dawnscientific.com.
If you have any questions or would like assistance selecting the right products for your application, our knowledgeable team is ready to help. Contact us at 1-800-DAWN-SCI (1-800-329-6724) or email sales@dawnscientific.com. We look forward to serving your laboratory and research needs.
Acetonitrile HPLC grade is used as a mobile phase solvent in HPLC, UHPLC, and LC-MS applications for pharmaceutical, research, and chemical analysis.
HPLC grade Acetonitrile provides ultra-high purity, low UV absorbance, and minimal impurities, helping achieve accurate and reproducible chromatographic results.
Our Acetonitrile HPLC grade has a purity level of ≥99.9%, ensuring optimal performance in chromatography applications.
Yes, Acetonitrile is widely used in HPLC applications because of its low viscosity, high volatility, and low background interference.
Acetonitrile generally offers lower backpressure, faster analysis time, better peak resolution, and lower UV cutoff compared to Methanol.
The UV cutoff of Acetonitrile is approximately 190 nm, making it suitable for UV and UV-Vis detection methods.
Yes, Acetonitrile is completely miscible with water and many organic solvents used in chromatography.
Acetonitrile HPLC is commonly available in laboratory and bulk pack sizes depending on analytical and industrial requirements. Contact Dawn Scientific for available packaging options.
Acetonitrile HPLC needs to be stored in a cool, dry place with below 25°C without the use of sunlight and igniting sources.
Dawn Scientific Acetonitrile HPLC offers high purity, reliable chromatographic performance, low impurity levels, and consistent quality for laboratory applications.
Yes, Acetonitrile HPLC grade complies with USP standards, making it suitable for pharmaceutical use.

Reviews (0)
Please Login