Buy Sirius Red (2610-10-8) MF: C45H26N10Na6O21S6 | MW: 1373.07. Get High Quality Sirius Red (2610-10-8) from TriStains at Dawnscientific.com
Sirius Red is a histological stain used to visualize collagen fibers in various tissues. It is a mixture of dyes, primarily Sirius Red F3B and Sirius Red 4B.
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Applications:
Collagen Visualization: Sirius Red is commonly used to stain collagen fibers in tissue sections. It selectively binds to collagen, resulting in a red or orange color under microscopy. It allows researchers to examine and quantify collagen content, distribution, and organization in different tissues, including skin, liver, heart, kidney, and lung.Fibrosis Assessment: Sirius Red staining is widely employed in the assessment of fibrosis, a pathological condition characterized by excessive collagen deposition in tissues. By staining collagen fibers, Sirius Red enables the evaluation of fibrotic changes and the extent of fibrosis in affected tissues. This staining technique is valuable in studying diseases such as liver fibrosis, pulmonary fibrosis, and cardiac fibrosis.Tissue Engineering and Regenerative Medicine: Sirius Red staining is also utilized in tissue engineering and regenerative medicine. It allows researchers to assess the deposition and remodeling of collagen fibers in engineered tissues and scaffold materials. This information helps evaluate the structural integrity and functional properties of engineered tissues.Research in Cancer and Tumor Microenvironment: The tumor microenvironment often exhibits alterations in collagen architecture and deposition. Sirius Red staining can be employed to investigate changes in collagen organization and density within tumor tissues. It provides insights into the tumor-stroma interaction and its impact on tumor progression and metastasis.Quantitative Analysis: Sirius Red staining can be combined with image analysis techniques to quantify collagen content and assess various parameters related to collagen structure, such as fiber thickness, density, and orientation. This quantitative analysis enables researchers to obtain objective measurements and compare collagen-related parameters between different samples or experimental conditions.
Sirius Red
Get High Quality Sirius Red (2610-10-8) from ChemieR at Dawn Scientific. M.F: C45H26N10Na6O21S6 | M.W.: 1373.07, Shop now for reliable and Reproducible results
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ADDITIONAL INFORMATION
Alternate Names | Direct red 80 |
Application | Sirius red is a cardiac muscle stain |
CAS Number | 2610-10-8 |
Molecular Weight | 1373.07 |
Molecular Formula: | C45H26N10Na6O21S6 |
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Sirius red is a dye useful as a cardiac muscle stain and as a model compound. As a model compound in adsorption studies, Sirius red has been utilized to compare efficacy of textile dye removal in aqueous solutions.
TECHNICAL INFORMATION
Appearance | Powder |
Physical State | Solid |
Solubility | Soluble in water (partly), ethanol (very slightly), and cellosolve (very slightly). Insoluble in many organic solvents. |
Storage | Store at 4° C |
SAFETY INFORMATION
WGK Germany | 3 |
PubChem CID | 9571131 |
Merck Index | 14: 8548 |
MDL Number | MFCD00054389 |
EC Number | 220-027-3 |
Beilstein Registry | 8185575 |
SMILES | C1=CC(=CC=C1N=NC2=CC(=C(C=C2)N/N=C/3C(=O) C4=C(C=C3S(=O)(=O)[O-])C=C(C=C4)NC(=O) NC5=CC6=C(C(=O)/C(=NNC7=C(C=C(C=C7) N=NC8=CC=C(C=C8)S(=O)(=O)[O-])S(=O)(=O)[O-]) /C(=C6)S(=O)(=O)[O-])C=C5)S(=O)(=O)[O-]) S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] |
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